Zingerone enhances glutamatergic spontaneous excitatory transmission by 1 activating TRPA 1 but not TRPV 1 channels in the adult rat substantia gelatinosa
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چکیده
Zingerone enhances glutamatergic spontaneous excitatory transmission by 1 activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa 2 3 Hai-Yuan Yue, Chung-Yu Jiang, Tsugumi Fujita, and Eiichi Kumamoto 4 5 Department of Physiology, Saga Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan 6 7 Running head: glutamatergic transmission enhancement by zingerone 8 9 Number of figures: 8; number of pages: 34; numbers of words for Abstract: 229 10 11 Hai-Yuan Yue and Chung-Yu Jiang contributed equally to this work. 12 13 Correspondence should be addressed to Eiichi Kumamoto, Department of Physiology, Saga 14 Medical School, 5-1-1 Nabeshima, Saga 849-8501, Japan. 15 Tel: 81-952-34-2273; Fax: 81-952-34-2013; E-mail: [email protected] 16 17 18 Articles in PresS. J Neurophysiol (May 8, 2013). doi:10.1152/jn.00754.2012
منابع مشابه
Zingerone enhances glutamatergic spontaneous excitatory transmission by activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa.
Transient receptor potential (TRP) channels are thought to play a role in regulating nociceptive transmission to spinal substantia gelatinosa (SG) neurons. It remains to be unveiled whether the TRP channels in the central nervous system are different in property from those involved in receiving nociceptive stimuli in the peripheral nervous system. We examined the effect of the vanilloid compoun...
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